The Application Layer
This is the only layer that directly interacts with data from the user. Software applications like web browsers and email clients rely on the application layer to initiate communications. But it should be made clear that client software applications are not part of the application layer; rather the application layer is responsible for the protocols and data manipulation that the software relies on to present meaningful data to the user. Application layer protocols include HTTP as well as SMTP (Simple Mail Transfer Protocol is one of the protocols that enables email communications).
The Presentation Layer
This layer is primarily responsible for preparing data so that it can be used by the application layer; in other words, layer 6 makes the data presentable for applications to consume. The presentation layer is responsible for translation, encryption, and compression of data.