Vantaggi
Their mission to help cancer patients and advance research. The people are pretty amazing there, but the culture corrupts even the best managers, who must bow to the queen--even when they try to convince themselves that they aren't doing it.
Svantaggi
It's really hard to write this because I love what I do, but the culture is pretty terrible here. You may luck out with a great manager and even a team that is top notch, but at every step, the company culture will sabotage your best efforts. There is dysfunction with no real effort to fix it. The decision to return to in-office was given like an edict, with promise of bringing in an outside consultant when employees voiced outrage at the first attempt. But they didn't consult the employees on these decisions, a missed opportunity for greatness because the employees are the best. Most of the times, people are running around in fear that they'll be called into the CEO's office and called into question for some minor thing or infraction that will seem like the biggest offense. It's a lot like a monarchy and the CEO gets to decide what to do--even if it has employees running around. If you want greatness, you might be able to pull it off at times, but it will be hard to achieve it because you will be constantly looking over your shoulder.